在网上查到关于H7N9禽流感最早的记录,来自美国卫生部,美国国家生物技术信息中心;时间:1988年,地点:美国明尼苏达州,感染动物:火鸡。科学杂志2006年某刊作为索引文献的15个作者中,6人姓名看起来是中国人。病毒的基因序列也列在文章中。网址如下:
http://www.ncbi.nlm.nih.gov/nuccore/CY014787.1Influenza A virus (A/turkey/Minnesota/1/1988(H7N9)) segment 7, complete sequence
GenBank: CY014787.1
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http://www.ncbi.nlm.nih.gov/nuccore/CY014787.1Influenza A virus (A/turkey/Minnesota/1/1988(H7N9)) segment 7, complete sequence
GenBank: CY014787.1
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LOCUS CY0147871027 bpcRNAlinear VRL 21-SEP-2006
DEFINITION Influenza A virus (A/turkey/Minnesota/1/1988(H7N9)) segment 7,
complete sequence.
ACCESSION CY014787
VERSION CY014787.1 GI:115278574
KEYWORDS.
SOURCE Influenza A virus (A/turkey/Minnesota/1/1988(H7N9))
ORGANISM Influenza A virus (A/turkey/Minnesota/1/1988(H7N9))
Viruses; ssRNA negative-strand viruses; Orthomyxoviridae;
Influenzavirus A.
REFERENCE 1 (bases 1 to 1027)
AUTHORS Obenauer,J.C., Denson,J., Mehta,P.K., Su,X., Mukatira,S.,
Finkelstein,D.B., Xu,X., Wang,J., Ma,J., Fan,Y., Rakestraw,K.M.,
Webster,R.G., Hoffmann,E., Krauss,S., Zheng,J., Zhang,Z. and
Naeve,C.W.
TITLE Large-scale sequence analysis of avian influenza isolates
JOURNAL Science 311 (5767), 1576-1580 (2006)
PUBMED 16439620
REFERENCE 2 (bases 1 to 1027)
AUTHORS Obenauer,J.C., Denson,J., Mehta,P.K., Su,X., Mukatira,S.,
Finkelstein,D.B., Xu,X., Wang,J., Ma,J., Fan,Y., Rakestraw,K.M.,
Webster,R.G., Hoffmann,E., Krauss,S., Zheng,J., Zhang,Z. and
Naeve,C.W.
TITLE Direct Submission
JOURNAL Submitted (13-SEP-2006) Hartwell Center for Bioinformatics &
Biotechnology, St. Jude Children's Research Hospital, 332 North
Lauderdale Str., Memphis, TN 38105, USA
FEATURES Location/Qualifiers
source 1..1027
/organism="Influenza A virus
(A/turkey/Minnesota/1/1988(H7N9))"
/mol_type="viral cRNA"
/strain="A/turkey/Minnesota/1/1988"
/serotype="H7N9"
/host="Avian"
/db_xref="taxon:402490"
/segment="7"
/country="USA: Minnesota"
/collection_date="13-Jul-1988"
primer_bind 1..15
/note="PCR amplification primer sequence"
gene26..1007
/gene="M2"
CDS join(26..51,740..1007)
/gene="M2"
/codon_start=1
/product="matrix protein 2"
/protein_id="ABI84696.1"
/db_xref="GI:115278576"
/translation="MSLLTEVETPTRNGWECKCSDSSDPLVIAASIIGILHLILWILD
RLFFKCIYRRLKYGLKRGPSTEGVPESMREEYRQEQQSAVDVDDGHFVNIELE"
gene26..784
/gene="M1"
CDS 26..784
/gene="M1"
/codon_start=1
/product="matrix protein 1"
/protein_id="ABI84695.1"
/db_xref="GI:115278575"
/translation="MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALME
WLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYRK
LKREITFHGAKEVALSYSTGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHR
SHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRT
IGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK"
primer_bind complement(1007..1027)
/note="PCR amplification primer sequence"
ORIGIN
1 agcaaaagca ggtagatatt gaaagatgag tcttctaacc gaggtcgaaa cgtacgttct
61 ctctatcgtc ccgtcaggcc ccctcaaagc cgagatcgcg cagagacttg aagatgtctt
121 tgcagggaag aacaccgatc ttgaggcact catggagtgg ctaaagacaa gaccaatcct
181 gtcacctctg accaagggga ttttaggatt tgtgtttacg ctcaccgtgc ccagtgagcg
241 aggactgcag cgtagacgct ttgtccaaaa tgcccttaat gggaatgggg atccaaacaa
301 catggacaga gcagtcaaac tatacaggaa actaaaaagg gaaataacat tccatggggc
361 aaaagaagta gcactcagtt attcaactgg tgcacttgcc agttgcatgg gcctcatata
421 caacagaatg gggactgtga ccaccgaagt ggcatttggc ctggtgtgcg ccacatgtga
481 gcagattgct gattcccagc atcggtctca cagacaaatg gtgacaacaa ccaacccact
541 aatcagacat gagaacagaa tggtactagc cagtactacg gctaaagcca tggagcaaat
601 ggcaggatca agtgagcaag cagcagaggc tatggaggtt gctagtcagg ctaggcaaat
661 ggtgcaggca atgaggacca ttggaactca tcctagctcc agtgctggtc taaaagatga
721 tcttcttgaa aatttgcagg cctaccagaa acggatggga gtgcaaatgc agcgattcaa
781 gtgatcctct cgttattgcc gcaagtatca ttgggatctt gcacttgata ttgtggattc
841 ttgatcgtct tttcttcaaa tgcatttatc gtcgccttaa atacggtttg aaaagagggc
901 cttctacgga aggagtgcct gagtctatga gggaagaata ccggcaggaa cagcagagtg
961 ctgtggatgt tgacgatggt cattttgtca acatagagct ggagtaaaaa actaccttgt
1021 ttctact
//
按时间顺序,倒序排列。
不知该数据库收集信息是否足够完备。
看了这信息排列,再想想前几天各位院士们的言论,真的再也不能高看他们了。
今后再有来势汹汹的、新型的、传染性病毒性疾病疫情发生,我们必须把生物战争打击的可能性放在疫情分析的首位。拒绝这样做,就是自愿挨打,就是热爱被打击,就是对中国人民的 犯罪。
2013:中国浙江/杭州 鸡(红血球凝集素)
2011:韩国 野鸭和spot-billed duck
(美)内布拉斯加 鹅、珍珠鸡
(美)密西西比 Northern shoverl
2009:捷克 大雁/鹅
2008:韩国 野鸭 (很多项)
西班牙 Anas crecca
危地马拉 blue-winged teal 蓝翼水鸭
蒙古国 野鸭
2007:(美)科罗拉多州 环境 (没有指明动物)
2006:(美)阿拉斯加 大雁
2005:西班牙 mallard 野鸭
2002:瑞典 2002 野鸭 (红血球凝集素)
2000:(美)特拉华 翻石鹬
1995:(美)特拉华 翻石鹬
1988:(美)明尼苏达 火鸡 (分析最详尽,条目数量最多)
该数据库中共提及两类病毒:N5N1(1条记录), H7N9(178条)。
H5N1:烟灰燕鸥 西澳大利亚,1983年。
.
一些动物名称,有待专业高人指定。